On Iterative Algorithms for Quantitative Photoacoustic Tomography in the Radiative Transport Regime

In this paper, we describe the numerical reconstruction method for quantitative photoacoustic tomography (QPAT) based on the radiative transfer equation (RTE), which models light propagation more accurately than diffusion approximation (DA). We investigate the reconstruction of absorption coefficient and/or scattering coefficient of biological tissues. Given the scattering coefficient, an improved fixed-point iterative method is proposed to retrieve the absorption coefficient for its cheap computational cost. And we prove the convergence. To retrieve two coefficients simultaneously, Barzilai-Borwein (BB) method is applied. Since the reconstruction of optical coefficients involves the solutions of original and adjoint RTEs in the framework of optimization, an efficient solver with high accuracy is improved from [15]. Simulation experiments illustrate that the improved fixed-point iterative method and the BB method are the comparative methods for QPAT in two cases.